International Journal of Cosmetics and Dermatology

Clinical role of oral vitamin C and E therapy in skin and hair disorders: A systematic review

Fiore Casale, Susie Suh, Katerina Yale, Natasha Atanaskova Mesinkovska

Vitamin C and E are generally recognized as safe dietary supplements that provide benefits for skin and hair health. However, their clinical validity in the treatment of dermatologic conditions has not been explored. It is highly important to review the current evidence on the therapeutic utility of oral vitamin C and E therapy for dermatologic disorders.

Type IV hypersensitivity to timolol

Silvio Espínola and Dory Mora

Glaucoma is characterized as an optic neuropathy determined by structural changes and functional deficiencies. Primary glaucoma (open-angle) is the most prevalent in the general population (40-80 years 3-4%), and it constitutes the leading cause of irreversible vision loss in industrialized countries (3).Current pharmacological treatments seek to obtain optimal local tolerance, using preservative-free formulations in simple presentations or combinations, both in single-dose and multi-dose.Contact dermatitis is caused by an ample inflammation which arises from the release of pro-inflammatory cytokines from keratinocytes, usually in response to chemical stimuli. Mainly, this causes alteration of the skin barrier, cellular changes at the epidermal level, and release of cytokines (4).Allergic contact dermatitis caused by eye medication is mainly attributed to active ingredients. But other excipient ingredients should also be analyzed in addition to the products on an "as is" basis (5).

Efficacy of Bastikarma in Vitiligo

Salim Musa Mulla

Glaucoma is characterized as an optic neuropathy determined by structural changes and functional deficiencies. Primary glaucoma (open-angle) is the most prevalent in the general population (40-80 years 3-4%), and it constitutes the leading cause of irreversible vision loss in industrialized countries (3).Current pharmacological treatments seek to obtain optimal local tolerance, using preservative-free formulations in simple presentations or combinations, both in single-dose and multi-dose.Contact dermatitis is caused by an ample inflammation which arises from the release of pro-inflammatory cytokines from keratinocytes, usually in response to chemical stimuli. Mainly, this causes alteration of the skin barrier, cellular changes at the epidermal level, and release of cytokines (4).Allergic contact dermatitis caused by eye medication is mainly attributed to active ingredients. But other excipient ingredients should also be analyzed in addition to the products on an "as is" basis (5).

Vitiligo Study in View of Familial Occurence

Salim Musa Mulla

I am enclosing herewith a manuscript (Research Article) entitled “Vitiligo- Study in view of Familial Occurance” for publication in (International Journal of Cosmetics And Dermatology) for possible evaluation. The corresponding author of this manuscript is (Dr. Salim Musa Mulla) and co-authors have been mentioned below according to their contribution. 

Manufacturing and formulation of natural products based on the Chitosan as active ingredient in the forms of gel and spray

Mohammadreza Gholibeikian, Zahra Nooriani, Amirhosein Firouzi, Nastaran Samali, Somayeh faraji, Afsaneh oshli

The purpose of this work is to make based on natural polysaccharide compounds such as chitosan for the microorganism test which led to the destruction of Escherichia coli bacteria, Candida albicans vegetative cells and Aspergillus niger spores and Herpes simplex virus (HSV-1). Chitosan products in the forms of gel and spray have bactericidal, fungicidal and virucidal properties as antiseptic products. Chitosan polysaccharides with high molecular weight are extracted from aquatic organisms such as shrimp. Physical and chemical analysis, identification test of Chitosan as active ingredient and also non-sensitizing test of these products in the forms of gel and spray have been done on the rabbit's skin that did not show no sensitivity and inflammation. It seems that natural products in the forms of gels and sprays based on chitosan, as alternative products for alcohol and chemical compounds, have a useful and promising role as antiseptic in eliminating bacteria, fungi and viruses left on the skin of the hands.

Keyword: Natural product, Chitosan polysaccharide, antiseptic, non-sensitizing test, inflammation. 

The formulation of moisturizing and hydrating cream based on natural ingredients such as chitosan

Mohammadreza Gholibeikian, Zahra Nooriani, Amirhosein Firouzi, Nastaran Samali

The purpose of this work is to make moisturizing and hydrating cream for the skin. the ingredients of moisturizing and hydrating cream are based on natural polysaccharides, such as chitosan and extracted from aquatic organisms such as shrimp. Physical and chemical analysis, identification test of the oils in the cream based on gas chromatography instrument have been done in the reference laboratory of Food and Drug Organization of Iran country. Also non-sensitizing test of the formulated cream have been done by the rabbit at department of pharmaceutics, school of pharmacy, Shahid Beheshti University of Medical Sciences in Iran country.